• Users Online: 397
  • Home
  • Print this page
  • Email this page
Home About us Editorial board Search Ahead of print Current issue Archives Submit article Instructions Subscribe Contacts Login 
ORIGINAL ARTICLE
Year : 2014  |  Volume : 42  |  Issue : 4  |  Page : 124-129

Three-dimensional power Doppler transrectal ultrasound: value in prediction of prostate cancer aggressiveness


1 Department of Radiology, Tanta University, Tanta, Egypt
2 Department of Urology, Tanta University, Tanta, Egypt

Correspondence Address:
Mohamed M Hefeda
2, Elbandar Square, 19991 Elmahalla ElKobra
Egypt
Login to access the Email id


DOI: 10.4103/1110-1415.145273

Rights and Permissions

Objective The aim of the study was to evaluate the role of three-dimensional power Doppler transrectal ultrasound in the diagnosis and prediction of aggressiveness of prostate cancer. Materials and methods A total of 93 patients were included in the study; all patients had abnormal digital rectal examination or high serum prostate-specific antigen or both. All patients underwent two-dimensional transrectal ultrasound (2D-TRUS), three-dimensional grey-scale transrectal ultrasound (3D-GS TRUS), and three-dimensional power Doppler sonography (3D-PDS). Vascular distribution patterns were evaluated according to the following grading system: I, regular and strip-shaped flow distribution in the peripheral zone (PZ) and/or transitional zone; II, asymmetric abundant flow with vascular disorganization in the PZ; and III, diffusely increased flow with vascular disorganization in the PZ and transitional zone. Grades II and III were regarded as abnormal, and grade I was considered to be normal. Target biopsies were obtained together with 12 core systematic biopsies. Pathological results were correlated with the imaging data. Results Fifty-six patients had prostate cancer, and 37 patients had no evidence of malignant prostatic disease. 3D-PDS had sensitivity of 76.6%, specificity 78.4%, positive predictive value of 84.3%, negative predictive value of 69%, and overall accuracy of 77.4% in differentiation between benign and malignant prostate. The vascular pattern correlated well with serum prostate-specific antigen, Gleason score, presence of metastasis, and local infiltration. Conclusion 3D-PDS improves accuracy of detection, local staging, and prediction of biological behavior of prostate cancer patients compared with 2D-TRUS and 3D-TRUS.


[FULL TEXT] [PDF]*
Print this article     Email this article
 Next article
 Previous article
 Table of Contents

 Similar in PUBMED
   Search Pubmed for
   Search in Google Scholar for
 Related articles
 Citation Manager
 Access Statistics
 Reader Comments
 Email Alert *
 Add to My List *
 * Requires registration (Free)
 

 Article Access Statistics
    Viewed1880    
    Printed52    
    Emailed1    
    PDF Downloaded115    
    Comments [Add]    

Recommend this journal