• Users Online: 1357
  • Home
  • Print this page
  • Email this page
Home About us Editorial board Search Ahead of print Current issue Archives Submit article Instructions Subscribe Contacts Login 
Year : 2019  |  Volume : 47  |  Issue : 1  |  Page : 21-26

Role of magnetic resonance spectroscopy in evaluation of breast masses

1 Radiodiagnosis and Medical Imaging Department, Tanta Cancer Center, Faculty of Medicine, Tanta University, Tanta, Egypt
2 Department of Radiodiagnosis and Medical Imaging, Faculty of Medicine, Tanta University, Tanta, Egypt
3 Department of Oncology Surgery, Faculty of Medicine, Tanta University, Tanta, Egypt

Correspondence Address:
Aya E Elkafas
Department of Radiodiagnosis and Medical Imaging, Tanta Cancer Center, Tanta, 31511 Gharbiya
Login to access the Email id

DOI: 10.4103/tmj.tmj_19_18

Rights and Permissions

Background Early detection followed by appropriate treatment is currently the most effective strategy to reduce breast cancer mortality. New techniques must provide more precise evaluation of the indeterminate lesions. Magnetic resonance spectroscopy (MRS) is one of the available new techniques on MRI. It represents a noninvasive and nonionizing method of characterizing a user-selected volume of tissue based on the metabolic (chemical) content. Aim The aim was to assess the role of in-vivo proton MRS in diagnosis, characterization, and differentiation between benign and malignant breast masses. Patients and methods In this study, 40 female patients were examined by MRI using the multiphase dynamic sequence and proton MRS using magnets of intensity field 1.5 Tesla systems. Single-voxel technique after adequate shimming was used. Results Thirty (62.5%) cases were malignant (based on the presence of high choline peak in the spectrum) and 18 (37.5%) cases were benign (no choline peak). MRS has increased the specificity of dynamic MRI for diagnosis of probable lesion from 76.5 to 94.1%. False-positive results were found in one case, and false-negative results were found in two cases. Conclusion In-vivo proton MRS is a powerful method for characterizing indeterminate breast lesions based on the presence of a high choline peak in the spectrum.

Print this article     Email this article
 Next article
 Previous article
 Table of Contents

 Similar in PUBMED
   Search Pubmed for
   Search in Google Scholar for
 Related articles
 Citation Manager
 Access Statistics
 Reader Comments
 Email Alert *
 Add to My List *
 * Requires registration (Free)

 Article Access Statistics
    PDF Downloaded120    
    Comments [Add]    

Recommend this journal